Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355152 | 0.85 | FASN (0.42) | FASN | |
| SCHEMBL2357731 | 0.81 | FASN (0.44) | FASN | |
| SCHEMBL2356751 | 0.81 | FASN (0.60) | FASN | |
| SCHEMBL2356332 | 0.78 | FASN (0.49) | FASN | |
| SCHEMBL15064546 | 0.77 | ALDH1A1 (0.34) | GAAALDH1A1MAPTHPGDAPOBEC3G | |
| SCHEMBL2357335 | 0.76 | FASN (0.61) | FASNHTT | |
| SCHEMBL14151928 | 0.74 | FASN (0.59) | FASNSMN1; SMN2GAAALDH1A1HTT | |
| SCHEMBL2358391 | 0.74 | FASN (0.53) | FASN | |
| SCHEMBL2355763 | 0.74 | FASN (0.46) | FASN | |
| SCHEMBL2301635 | 0.73 | FASN (0.57) | FASNGAAALDH1A1HTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |