SCHEMBL23565002

SCHEMBL23565002

O=C(CBr)NCc1ccc(Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.66
MEN1 O00255 4/20 0.66
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
ALDH1A1 P00352 3/20 0.60
HPGD P15428 3/20 0.60
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.54
THRB P10828 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
POLB P06746 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
ERCC1 P07992 1/20 0.53
ERCC4 Q92889 1/20 0.53
PKM P14618 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692807 0.82 KMT2A (0.68) KMT2AMEN1CYP2C9CYP2C19ALDH1A1
SCHEMBL16082991 0.82 ALDH1A1 (0.83) KMT2AMEN1CYP2C9CYP2C19ALDH1A1
SCHEMBL32665587 0.82 TRPV1 (0.54) KMT2AMEN1GAAL3MBTL1
SCHEMBL28822072 0.82 L3MBTL1 (0.64) KMT2AMEN1ALDH1A1HPGDGAA
SCHEMBL4035227 0.82 KMT2A (0.68) KMT2AMEN1CYP2C9CYP2C19ALDH1A1
SCHEMBL4268220 0.81 LMNA (0.62) KMT2ACYP2C19ALDH1A1HPGDRAB9A
SCHEMBL1709315 0.81 HPGD (0.70) KMT2AMEN1CYP2C9CYP2C19ALDH1A1
SCHEMBL4406319 0.81 LMNA (0.68) KMT2AALDH1A1HPGDRAB9APOLB
SCHEMBL20740269 0.81 LMNA (0.68) KMT2AALDH1A1HPGDRAB9APOLB
SCHEMBL14678185 0.81 KMT2A (0.59) KMT2AMEN1ALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698170-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS Eberhard-Karls-Universität Tübingen (DE) 2026-02-25 EP disclosed
WO-2024218333-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) 2024-10-24 WO disclosed
CN-114787145-B Benzamide derivatives as transforming growth factor-beta receptor I/ALK5 inhibitors 阿戈麦布西班牙股份有限公司 2024-03-26 CN disclosed
CN-116963733-A Imidazole compounds as ENPP1 inhibitors 斯汀格瑞治疗股份有限公司 2023-10-27 CN disclosed
EP-4255425-A1 IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 Stingray Therapeutics, Inc. (US) 2023-10-11 EP disclosed
CN-114787145-A Benzamide derivatives as transforming growth factor-beta receptor I/ALK5 inhibitors 奥里戈生物制药有限公司 2022-07-22 CN disclosed
WO-2022119928-A1 IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 Stingray Therapeutics, Inc. (US) 2022-06-09 WO disclosed
WO-2022119928-A1 IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 Stingray Therapeutics, Inc. (US) 2022-06-09 WO disclosed
WO-2021127459-A1 GPR139 RECEPTOR MODULATORS BLACKTHORN THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed