⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573151 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL31485576 | 0.73 | TRIM24 (0.30) | — | |
| SCHEMBL25262187 | 0.73 | CTSK (0.30) | — | |
| SCHEMBL1392715 | 0.69 | — | — | |
| SCHEMBL14791364 | 0.69 | — | — | |
| SCHEMBL15181868 | 0.69 | — | — | |
| SCHEMBL18770239 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL8997696 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL27124482 | 0.68 | — | — | |
| SCHEMBL26983569 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230280220-A1 | Benzimidazole Derivative Compounds and Uses Thereof | PFIZER INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | PFIZER INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210188829-A1 | Chemical Compounds | PFIZER INC. (US) | 2021-06-24 | — | — | US | disclosed |