⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25219744 | 0.78 | — | — | |
| SCHEMBL31485556 | 0.74 | — | — | |
| SCHEMBL27124936 | 0.74 | — | — | |
| SCHEMBL26983624 | 0.74 | — | — | |
| SCHEMBL19214044 | 0.70 | — | — | |
| SCHEMBL23055685 | 0.69 | — | — | |
| SCHEMBL27132516 | 0.68 | — | — | |
| SCHEMBL1502910 | 0.67 | — | — | |
| SCHEMBL25802351 | 0.67 | — | — | |
| SCHEMBL11102160 | 0.67 | HSD11B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230280220-A1 | Benzimidazole Derivative Compounds and Uses Thereof | PFIZER INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | PFIZER INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210188829-A1 | Chemical Compounds | PFIZER INC. (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2021124155-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. (US) | 2021-06-24 | — | — | WO | disclosed |