Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.60 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566116 | 0.85 | PRSS1 (0.65) | PRSS1MRGPRX1F2F10F7 | |
| SCHEMBL23565993 | 0.85 | KLK1 (0.49) | PRSS1F2KLK1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL23235770 | 0.84 | PRSS1 (0.66) | PRSS1MRGPRX1F2F10F7 | |
| Hydrochloric Acid SCHEMBL23541011 | 0.84 | F2 (0.50) | PRSS1F2KLK1PRSS2PRSS3 | |
| SCHEMBL5759617 | 0.81 | PRSS1 (0.70) | PRSS1MRGPRX1F2F10F7 | |
| SCHEMBL10921622 | 0.80 | PRSS1 (0.65) | PRSS1MRGPRX1F2F10F7 | |
| SCHEMBL23566126 | 0.80 | PRSS1 (0.77) | PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL23541001 | 0.79 | PRSS1 (0.74) | PRSS1F2PRSS2PRSS3 | |
| SCHEMBL23566304 | 0.77 | PRSS1 (0.54) | PRSS1MRGPRX1F2F10F7 | |
| SCHEMBL3368852 | 0.77 | PRSS1 (0.77) | PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
| WO-2021127452-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | PRSS1 652/4885MRGPRX1 381/4885F2 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.