Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | F7 | P08709 | 4/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566116 | 0.91 | PRSS1 (0.65) | PRSS1F2F10F7PRSS2 | |
| Hydrochloric Acid SCHEMBL23235770 | 0.89 | PRSS1 (0.66) | PRSS1F2F10F7PRSS2 | |
| SCHEMBL23901895 | 0.78 | KLK1 (0.55) | PRSS1F2PRSS2PRSS3KLK1 | |
| SCHEMBL23565995 | 0.77 | PRSS1 (0.60) | PRSS1F2F10F7PRSS2 | |
| SCHEMBL23902235 | 0.77 | NPC1 (0.49) | PRSS1F2F10F7MRGPRX1 | |
| SCHEMBL5759617 | 0.76 | PRSS1 (0.70) | PRSS1F2F10F7PRSS2 | |
| SCHEMBL23901830 | 0.76 | NPC1 (0.47) | PRSS1F2F10F7MRGPRX1 | |
| SCHEMBL10921622 | 0.75 | PRSS1 (0.65) | PRSS1F2F10F7MRGPRX1 | |
| SCHEMBL23565999 | 0.75 | KLK1 (0.52) | PRSS1F2PRSS2PRSS3KLK1 | |
| SCHEMBL23902221 | 0.75 | RAB9A (0.47) | PRSS1F2F10F7PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127452-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | WO | disclosed |