Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23235893 | 0.99 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL23901783 | 0.87 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL23901802 | 0.86 | FFAR4 (0.47) | PRSS1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL23880720 | 0.86 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL23902221 | 0.86 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL23235737 | 0.85 | FFAR4 (0.46) | PRSS1F2MRGPRX4 | |
| Hydrochloric Acid SCHEMBL23880744 | 0.85 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL23566116 | 0.84 | PRSS1 (0.65) | PRSS1MRGPRX1F2F10F7 | |
| SCHEMBL23902235 | 0.83 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL23235770 | 0.83 | PRSS1 (0.66) | PRSS1MRGPRX1F2F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | NPC1 1939/4885RAB9A 1026/4885SMN1; SMN2 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.