Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566358 | 0.82 | GAA (0.41) | NOS3NOS1NOS2MAOAMAOB | |
| SCHEMBL8288513 | 0.79 | MAOA (0.35) | MAOAMAOBPARP1DYRK1ADYRK1B | |
| SCHEMBL19153122 | 0.79 | MAOA (0.41) | MAOAMAOBDYRK1ADYRK1BDYRK2 | |
| SCHEMBL18238925 | 0.76 | MAOA (0.36) | MAOAMAOBDYRK1ADYRK1BDYRK2 | |
| SCHEMBL6702940 | 0.74 | NOS3 (0.46) | NOS3NOS1NOS2PARP1DYRK1A | |
| SCHEMBL23566387 | 0.74 | NOS3 (0.46) | NOS3NOS1NOS2DYRK1BF12 | |
| SCHEMBL30067771 | 0.74 | NOS3 (0.46) | NOS3NOS1NOS2PARP1DYRK1A | |
| SCHEMBL23566351 | 0.73 | HSP90AA1 (0.35) | MAOAMAOBDYRK1ADYRK1BDYRK2 | |
| SCHEMBL4474329 | 0.72 | MAOA (0.33) | MAOAMAOBDYRK1ADYRK1B | |
| SCHEMBL18640786 | 0.71 | NOS3 (0.52) | NOS3NOS1NOS2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | claimed |
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |