Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566424 | 0.90 | LMNA (0.62) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL23566386 | 0.82 | KDM4E (0.78) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL28995203 | 0.80 | LMNA (0.56) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL3771751 | 0.77 | RAB9A (0.74) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL21265743 | 0.74 | EHMT2 (0.51) | KDM4EHSD17B10RAB9ANPSR1CYP1A2 | |
| SCHEMBL11224973 | 0.73 | RAB9A (0.51) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL8423594 | 0.72 | CYP1A2 (1.00) | KDM4EHSD17B10POLBNPSR1CYP1A2 | |
| SCHEMBL31189925 | 0.72 | SMN1; SMN2 (0.65) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| SCHEMBL23566409 | 0.71 | KDM4E (0.80) | KDM4EHSD17B10POLBRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL7181225 | 0.71 | KDM4E (0.67) | KDM4EHSD17B10RAB9ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |