Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497263 | 0.83 | LMNA (0.69) | LMNASMN1; SMN2POLBCYP1A2CYP2C9 | |
| SCHEMBL23566386 | 0.81 | KDM4E (0.78) | LMNASMN1; SMN2POLBNPSR1KDM4E | |
| SCHEMBL23566367 | 0.80 | KDM4E (0.59) | LMNASMN1; SMN2POLBNPSR1KDM4E | |
| SCHEMBL17824280 | 0.77 | LMNA (0.61) | LMNASMN1; SMN2POLBCYP1A2CYP2C9 | |
| SCHEMBL12501224 | 0.77 | HDAC1 (0.56) | LMNANPSR1L3MBTL1MMP2TP53 | |
| SCHEMBL3771751 | 0.76 | RAB9A (0.74) | LMNASMN1; SMN2POLBNPSR1KDM4E | |
| SCHEMBL26619060 | 0.76 | TSHR (0.51) | LMNASMN1; SMN2POLBNPSR1KDM4E | |
| SCHEMBL6325602 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBNPSR1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL30282138 | 0.74 | KDM4E (0.61) | LMNASMN1; SMN2POLBNPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL29205457 | 0.74 | KDM4E (0.61) | LMNASMN1; SMN2POLBNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272363-B | Silicone-organic copolymers, sealants including silicone-organic copolymers, and related methods | 美国陶氏有机硅公司 | 2023-02-17 | — | — | CN | disclosed |