Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23564686 | 0.77 | ABL1 (0.36) | MAPTGAAMAPK1 | |
| SCHEMBL29760450 | 0.75 | FSCN1 (0.42) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL23525025 | 0.75 | FSCN1 (0.42) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL23525133 | 0.75 | CD44 (0.35) | KDM4EMAPTGAAMAPK1 | |
| SCHEMBL736818 | 0.68 | LMNA (0.59) | NPSR1LMNAHTTMAPTPOLB | |
| SCHEMBL13052609 | 0.67 | LMNA (0.42) | NPSR1LMNAHTTKDM4EMAPT | |
| SCHEMBL31286736 | 0.67 | HTT (0.35) | NPSR1LMNAHTTKDM4EMAPT | |
| SCHEMBL23524862 | 0.66 | ITK (0.44) | — | |
| SCHEMBL23524864 | 0.66 | ITK (0.44) | — | |
| SCHEMBL9633159 | 0.65 | LMNA (0.42) | NPSR1LMNAHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021124155-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. (US) | 2021-06-24 | — | — | WO | disclosed |