SCHEMBL13052609

SCHEMBL13052609

CC(C)OC(=O)N(C)c1nc(N(C)C(=O)OC(C)C)nc(N(C)C(=O)OC(C)C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
HTT P42858 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.37
KDM4E B2RXH2 2/20 0.33
USP2 O75604 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SYK P43405 2/20 0.33
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP7 P55210 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 3/20 0.31
CA1 P00915 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13052606 0.94 LMNA (0.42) LMNAHTTNPSR1ALDH1A1TSHR
SCHEMBL13052621 0.88 POLB (0.40) LMNAHTTNPSR1ALDH1A1TSHR
SCHEMBL13052608 0.88 ALDH1A1 (0.41) LMNAHTTNPSR1ALDH1A1SYK
SCHEMBL13052607 0.84 ALDH1A1 (0.45) LMNAHTTNPSR1ALDH1A1KDM4E
SCHEMBL13052601 0.83 POLB (0.44) LMNAHTTNPSR1ALDH1A1TSHR
SCHEMBL3641200 0.75 TSHR (0.43) LMNAHTTNPSR1ALDH1A1TSHR
SCHEMBL6244866 0.71
SCHEMBL12022850 0.70 TSHR (0.40) LMNANPSR1ALDH1A1TSHRKDM4E
SCHEMBL3507290 0.69 LMNA (0.58) LMNAHTTNPSR1ALDH1A1TSHR
SCHEMBL25081069 0.67 LIPE (0.47) LMNAHTTNPSR1HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160383-B1 N, N',N''-TRIMETHYL-N, N', N''-TRIS(METHOXYCARBONYL)-MELAMINE DERIVATIVES AND SIMILAR TRIAZINE DERIVATIVES FOR AS CROSS-LINKERS AND/OR BINDERS IN COATING COMPOUNDS, PAINTS, INKS, COMPOSITE MATERIALS AND LAMINATES BOREALIS AGROLINZ MELAMINE (AT) 2016-03-09 EP disclosed
US-8569423-B2 Triazine derivatives and a method for their production BOREALIS AGROLINZ MELAMINE GMBH (AT) 2013-10-29 US disclosed
US-8569423-B2 Triazine derivatives and a method for their production BOREALIS AGROLINZ MELAMINE GMBH (AT) 2013-10-29 US disclosed
US-20100292409-A1 Triazine Derivatives and a Method for Their Production BOREALIS AGROLINZ MELAMINE GMBH (AU) 2010-11-18 US disclosed
US-20100292409-A1 Triazine Derivatives and a Method for Their Production BOREALIS AGROLINZ MELAMINE GMBH (AU) 2010-11-18 US disclosed
WO-2008145704-A1 N, N',N''-TRIMETHYL-N, N', N''-TRIS(METHOXYCARBONYL)-MELAMINE DERIVATIVES AND SIMILAR TRIAZINE DERIVATIVES FOR AS CROSS-LINKERS AND/OR BINDERS IN COATING COMPOUNDS, PAINTS, INKS, COMPOSITE MATERIALS AND LAMINATES BOREALIS AGROLINZ MELAMINE GMBH (AT) 2008-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292409-A1 Triazine Derivatives and a Method for Their Production CYP3A5, CYP4Z1, IL5 LMNA 4710/4885HTT 1488/4885NPSR1 670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.