Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16549320 | 0.86 | PIK3CD (0.45) | PIK3CD | |
| SCHEMBL12339286 | 0.81 | SLC6A2 (0.38) | PIK3CDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21058885 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4BRD4SLC6A3 | |
| SCHEMBL29897978 | 0.79 | BRD4 (0.38) | BRD4ITGB3ITGA2B | |
| SCHEMBL3991707 | 0.79 | GNAO1 (0.38) | SLC6A2SLC6A4BRD4ITGB3ITGA2B | |
| SCHEMBL23559993 | 0.78 | NCF1 (0.41) | PIK3CD | |
| SCHEMBL3997177 | 0.77 | BRD4 (0.37) | SLC6A2SLC6A4BRD4ITGB3ITGA2B | |
| SCHEMBL25602526 | 0.77 | GNAO1 (0.40) | SLC6A2SLC6A4BRD4ITGB3ITGA2B | |
| SCHEMBL104444 | 0.76 | GNAO1 (0.37) | SLC6A2SLC6A4SLC6A3ITGB3ITGA2B | |
| SCHEMBL249671 | 0.76 | SIGMAR1 (0.42) | SLC6A4BRD4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192578-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2021127190-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |