Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23569929 | 1.00 | NR3C1 (0.46) | NR3C1PGRARALDH1A1CYP3A4 | |
| SCHEMBL23569958 | 0.86 | NR3C1 (0.34) | NR3C1PGRARALDH1A1CYP3A4 | |
| SCHEMBL23569953 | 0.75 | NR3C1 (0.56) | NR3C1PGRAR | |
| SCHEMBL23569510 | 0.75 | NR3C1 (0.56) | NR3C1PGRAR | |
| SCHEMBL23569287 | 0.75 | NR3C1 (0.56) | NR3C1PGRAR | |
| SCHEMBL23569233 | 0.75 | NR3C1 (0.56) | NR3C1PGRAR | |
| SCHEMBL26530418 | 0.75 | NR3C1 (0.61) | NR3C1PGRAR | |
| SCHEMBL26530431 | 0.75 | NR3C1 (0.61) | NR3C1PGRAR | |
| SCHEMBL25458875 | 0.74 | NR3C1 (0.37) | NR3C1PGRAR | |
| SCHEMBL23569548 | 0.72 | NR3C1 (0.58) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400607-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2024-12-05 | — | — | US | disclosed |
| US-12065465-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2024-08-20 | — | — | US | disclosed |
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2023-05-18 | — | — | US | disclosed |
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2023-05-18 | — | — | US | disclosed |
| US-11512107-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-11-29 | — | — | US | disclosed |
| US-11512107-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-11-29 | — | — | US | disclosed |
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE | 2021-10-21 | — | — | US | disclosed |
| US-20210188898-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | C9, NDC1, RTCB | NR3C1 3156/4885PGR 4678/4885AR 3914/4885 |
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | CYP17A1, HSD17B7, CYP11A1 | NR3C1 94/4885PGR 1661/4885AR 487/4885 |
| US-12065465-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | C9, NDC1, RTCB | NR3C1 3156/4885PGR 4678/4885AR 3914/4885 |
| US-20210188898-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | C9, NDC1, RTCB | NR3C1 3156/4885PGR 4678/4885AR 3914/4885 |
| US-11512107-B2 | Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation | C9, NDC1, RTCB | NR3C1 3156/4885PGR 4678/4885AR 3914/4885 |
| US-20240400607-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | C9, NDC1, RTCB | NR3C1 3156/4885PGR 4678/4885AR 3914/4885 |
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | CYP17A1, HSD17B7, CYP11A1 | NR3C1 94/4885PGR 1661/4885AR 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.