SCHEMBL23569064

SCHEMBL23569064

N#Cc1cc(S(=N)(N)=O)cs1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.34
S100A9 P06702 1/20 0.34
CA2 P00918 4/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23531763 0.84 CA2 (0.41) S100A9CA2CA12CA1CA9
SCHEMBL23569862 0.76 S100A9 (0.35) IKBKBS100A9NR3C1PGRNR3C2
SCHEMBL23569072 0.72 CA2 (0.39) CA2CA12CA1CA9
Hydrochloric Acid SCHEMBL31601091 0.71 DAO (0.35) CA2CA12CA1CA9
SCHEMBL23569878 0.69 S100A9 (0.31) S100A9
SCHEMBL23569065 0.68 CA2 (0.34) CA2CA12CA1CA9
SCHEMBL3189246 0.66
Hydrochloric Acid SCHEMBL11189447 0.64
Methane SCHEMBL27503900 0.64
SCHEMBL1492367 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021123237-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2021-06-24 WO disclosed