SCHEMBL23569072

SCHEMBL23569072

Cc1cc(S(=N)(N)=O)cs1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.39
DAO P14920 1/20 0.36
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2007922 0.83 CA2 (0.44) CA2DAOCA12CA1CA3
SCHEMBL16288940 0.76 DAO (0.40) CA2DAO
SCHEMBL11475698 0.74 DAO (0.39) CA2DAO
SCHEMBL2567368 0.74 DAO (0.43) CA2DAO
Hydrochloric Acid SCHEMBL31601091 0.73 DAO (0.35) CA2DAOCA12CA1CA3
SCHEMBL2173431 0.72 DAO (0.42) CA2DAO
Lithium Ion SCHEMBL2173434 0.72 LMNA (0.42) CA2DAO
SCHEMBL23569064 0.72 IKBKB (0.34) CA2CA12CA1CA9
SCHEMBL8493663 0.68 HTR6 (0.54) CA2DAO
SCHEMBL23569221 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021123237-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2021-06-24 WO disclosed