SCHEMBL2356935

SCHEMBL2356935

C=CCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.50
MMP3 P08254 7/20 0.49
HRH3 Q9Y5N1 5/20 0.46
HRH2 P25021 4/20 0.46
HRH1 P35367 4/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
MMP13 P45452 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
MAOB P27338 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1400344 0.94 CA1 (0.50) MMP2MMP3HRH3CA12CA1
SCHEMBL10452305 0.88 MMP2 (0.41) MMP2MMP3HRH3HRH2HRH1
SCHEMBL9065504 0.86 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL472165 0.86 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL9469380 0.86 SLC6A2 (0.47) MMP2MMP3
SCHEMBL11129382 0.85 MMP2 (0.51) MMP2MMP3HRH3HRH2HRH1
SCHEMBL10581417 0.84 MMP2 (0.48) MMP2MMP3MMP1MMP9MMP13
SCHEMBL5855876 0.84 MMP2 (0.48) MMP2MMP3MMP1MMP9MMP13
SCHEMBL10451577 0.84 ALDH1A1 (0.39) MMP2MMP3HRH3HRH2HRH1
SCHEMBL9469936 0.84 CLK4 (0.45) MMP2HRH2HRH1MMP13CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927823-B1 Method for alignment of liquid crystals using irradiated liquid crystal films KENT STATE UNIVERSITY (US) 2005-08-09 US claimed
JP-9013035-A None JP disclosed
JP-1075459-A None JP disclosed
JP-4217989-A None JP disclosed
JP-60013729-A None JP disclosed
CN-110199007-B Non-linear side chain liquid crystalline polyorganosiloxanes, method for the production thereof and use thereof in electro-optical applications and devices 美国陶氏有机硅公司 2023-02-28 CN disclosed
US-11001758-B2 Non-linear side chain liquid crystal polyorganosiloxanes and methods for their preparation and use in electro-optic applications and devices DOW SILICONES CORPORATION (US) 2021-05-11 US disclosed
US-20190144752-A1 NON-LINEAR SIDE CHAIN LIQUID CRYSTAL POLYORGANOSILOXANES AND METHODS FOR THEIR PREPARATION AND USE IN ELECTRO-OPTIC APPLICATIONS AND DEVICES DOW CORNING (US) 2019-05-16 US disclosed
WO-2017213809-A1 NON-LINEAR SIDE CHAIN LIQUID CRYSTAL POLYORGANOSILOXANES AND METHODS FOR THEIR PREPARATION AND USE IN ELECTRO-OPTIC APPLICATIONS AND DEVICES DOW CORNING CORPORATION (US) 2017-12-14 WO disclosed
EP-1355971-B1 PHOTOSENSITIVE POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS ELSICON INC (US) 2014-06-25 EP disclosed
WO-1989009426-A1 LIQUID CRYSTAL COLOUR DISPLAYS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1989-10-05 WO disclosed
US-4840693-A Organopolysiloxane hot-melt adhesive TORAY SILICONE CO., LTD. (JP) 1989-06-20 US disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed
EP-0300821-A2 Method of adhesion using organopolysiloxane hot-melt adhesive TORAY SILICONE COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
EP-0291884-A2 Organopolysiloxanes which exhibit liquid crystallinity at low temperatures, and a method for their preparation TORAY SILICONE COMPANY, LIMITED (JP) 1988-11-23 EP disclosed
JP-S6013729-A LIQUID CRYSTAL SUBSTANCE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP 1985-01-24 JP disclosed
US-RE31715-E ESTERS OF 2-METHYLBUTYLPHENOL THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1984-10-30 US disclosed
EP-0047453-B1 4'-(BETA-ALKYLOXYETHOXY)-4-CYANOBIPHENYL Chisso Corporation (JP) 1984-02-08 EP disclosed
US-4374748-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1983-02-22 US disclosed
US-4195916-A ELECTROOPTIC DISPLAY DEVICES, OPTICAL PHENOLIC ESTERS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1980-04-01 US disclosed