Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 6/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581417 | 1.00 | MMP2 (0.48) | MMP2MAPTALDH1A1MMP3MMP1 | |
| SCHEMBL2364296 | 0.96 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP2D6HIF1A | |
| SCHEMBL2831629 | 0.96 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP2D6HIF1A | |
| SCHEMBL6394837 | 0.90 | ALDH1A1 (0.51) | MAPTALDH1A1CYP1A2CYP2D6HIF1A | |
| SCHEMBL9650787 | 0.88 | POLB (0.46) | MMP2MAPTALDH1A1MMP3MMP1 | |
| SCHEMBL18777291 | 0.86 | ALDH1A1 (0.56) | MMP2MAPTALDH1A1MMP3MMP1 | |
| SCHEMBL7619158 | 0.86 | NPC1 (0.52) | MAPTALDH1A1POLBADRB2ADRB1 | |
| SCHEMBL8026374 | 0.86 | NPC1 (0.52) | MAPTALDH1A1POLBADRB2ADRB1 | |
| SCHEMBL11786917 | 0.86 | F2 (0.47) | MMP2MAPTALDH1A1MMP3MMP1 | |
| SCHEMBL8825667 | 0.85 | BACE1 (0.52) | MAPTLMNAPOLBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001648-B2 | Glassy chiral-nematic liquid crystals and optical devices containing same | UNIVERSITY OF ROCHESTER (US) | 2006-02-21 | — | — | US | claimed |
| US-20050263741-A1 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | NATIONAL SCIENCE FOUNDATION | 2005-12-01 | — | — | US | claimed |
| WO-2004083335-A2 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | UNIVERSITY OF ROCHESTER (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2019037613-A1 | A METHOD FOR PREPARING MONODISPERSED POLYMER MICROPARTICLES | SMART LIQUID CRYSTAL TECHNOLOGIES CO., LTD. (CN) | 2019-02-28 | — | — | WO | disclosed |
| US-7396486-B2 | Polymerizable mixtures | WACKER CHEMIE AG (DE) | 2008-07-08 | — | — | US | disclosed |
| US-7396486-B2 | Polymerizable mixtures | WACKER CHEMIE AG (DE) | 2008-07-08 | — | — | US | disclosed |
| US-7001648-B2 | Glassy chiral-nematic liquid crystals and optical devices containing same | UNIVERSITY OF ROCHESTER (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050263741-A1 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | NATIONAL SCIENCE FOUNDATION | 2005-12-01 | — | — | US | disclosed |
| WO-2004083335-A2 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | UNIVERSITY OF ROCHESTER (US) | 2004-09-30 | — | — | WO | disclosed |