Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568855 | 0.76 | TXNRD1 (0.32) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23569221 | 0.73 | — | — | |
| SCHEMBL23569213 | 0.72 | — | — | |
| SCHEMBL23569214 | 0.72 | — | — | |
| SCHEMBL23569310 | 0.72 | — | — | |
| SCHEMBL23569876 | 0.71 | — | — | |
| SCHEMBL20681368 | 0.71 | KIT (0.31) | — | |
| SCHEMBL23569880 | 0.71 | ACLY (0.30) | — | |
| SCHEMBL23569831 | 0.70 | HPGD (0.36) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL24429403 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123237-A1 | 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE | Oxford Drug Design Limited (GB) | 2021-06-24 | — | — | WO | disclosed |