SCHEMBL2357

SCHEMBL2357

[NH]CCc1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6315983 0.84 FFAR1 (0.54)
SCHEMBL130390 0.82 SIGMAR1 (0.54)
SCHEMBL132471 0.80 MAOA (0.58)
Benzene SCHEMBL3440179 0.79 ALDH1A1 (0.69)
SCHEMBL62125 0.79 ALDH1A1 (0.69)
SCHEMBL9741303 0.79 ALDH1A1 (0.69)
SCHEMBL133038 0.78 SIGMAR1 (0.58)
SCHEMBL130278 0.78 SIGMAR1 (0.58)
SCHEMBL7223041 0.78 FFAR1 (0.58)
SCHEMBL25402413 0.76 ALDH1A1 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3554 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043636-B2 Method for producing triarylorganoborates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-07-23 US claimed
WO-2024150963-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 광주과학기술원 2024-07-18 WO claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
CN-114920722-B 7-hydroxy-3-acetyl coumarin oxime compound, preparation method and medical application thereof 何黎琴 2024-03-08 CN claimed
CN-117586246-A NO donor coumarin Mannich base compound and preparation method and application thereof 安徽中医药大学 2024-02-23 CN claimed
CN-117567303-A Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof 安徽中医药大学 2024-02-20 CN claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 EP claimed
WO-2024005526-A1 NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 동국대학교 산학협력단 2024-01-04 WO claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
WO-2023150618-A2 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2023-08-10 WO claimed
US-4276297-A ANTIULCER AGENTS PFIZER INC. (US) 1981-06-30 US claimed
US-4258181-A BACTERICIDES, AMTITUMOR AGENTS, ANTICARCINOGENIC AGENTS AMERICAN CYANAMID COMPANY (US) 1981-03-24 US claimed
US-4235996-A BACTERICIDES, ANTITUMOR, ANTICANCER AMERICAN CYANAMID COMPANY (US) 1980-11-25 US claimed
US-4207320-A FUNGICIDES WARNER-LAMBERT COMPANY (US) 1980-06-10 US claimed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US claimed
US-4096143-A Process for producing phthalazinone and derivatives of the same FUJI PHOTO FILM CO., LTD. (JA) 1978-06-20 US claimed
US-4055553-A GLYCINE-ALANINE, POLYPEPTIDE, GROWTH HORMONE RELEASE INHIBITOR ION AMERICAN HOME PRODUCTS CORPORATION (US) 1977-10-25 US claimed
US-4016263-A BACTERICIDES BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US claimed
US-3991041-A GROWTH HORMONE RELEASE INHIBITOR AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-09 US claimed
US-3933803-A ANTIBACTERIAL, ANTIMITOTIC, ANTIMYCOTIC INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) 1976-01-20 US claimed