Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208264 | 0.83 | FPR2 (0.37) | FPR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3380255 | 0.80 | — | — | |
| SCHEMBL13160609 | 0.79 | FPR2 (0.35) | ALDH1A1TDP1FPR2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7007371 | 0.78 | ARG1 (0.41) | LMNAFPR2CHRNB2CHRNA4CHRNB4 | |
| Hydrochloric Acid SCHEMBL7007375 | 0.78 | ARG1 (0.41) | LMNAFPR2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19750305 | 0.76 | CHRNB4 (0.43) | FPR2CHRNB4CHRNA3KMT2ASMYD3 | |
| Hydrochloric Acid SCHEMBL7009720 | 0.75 | ARG1 (0.43) | FPR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL7009716 | 0.75 | ARG1 (0.43) | FPR2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL25161166 | 0.73 | KDM4E (0.37) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL21655188 | 0.72 | FPR2 (0.39) | MAPTALDH1A1LMNAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188789-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188789-A1 | ISOXAZOLINE DERIVATIVES | CYP3A7, CYP4X1, SIRT7 | MAPT 3340/4885ALDH1A1 1058/4885LMNA 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.