Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032204 | 0.95 | ADRA1D (0.36) | ADRA1DSIGMAR1BDKRB1MEN1KMT2A | |
| SCHEMBL24179985 | 0.95 | ADRA1D (0.36) | ADRA1DSIGMAR1BDKRB1MEN1KMT2A | |
| SCHEMBL21032699 | 0.81 | SLC6A2 (0.35) | SIGMAR1MEN1KMT2AGPR3SLC10A2 | |
| SCHEMBL2355589 | 0.76 | ADRA1D (0.40) | ADRA1D | |
| SCHEMBL2354383 | 0.76 | CA1 (0.36) | ADRA1D | |
| SCHEMBL2347270 | 0.76 | GRIA1 (0.35) | ADRA1D | |
| SCHEMBL2354707 | 0.76 | CA1 (0.41) | ADRA1D | |
| SCHEMBL2355164 | 0.76 | CA1 (0.41) | ADRA1DSLC10A2 | |
| SCHEMBL2351592 | 0.76 | CA1 (0.42) | ADRA1DSLC10A2 | |
| SCHEMBL2357565 | 0.76 | GRIA2 (0.43) | ADRA1DSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |