Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353940 | 0.90 | GRIA2 (0.48) | GRIA2GALR1NPC1SLC10A2MTNR1A | |
| SCHEMBL2353944 | 0.89 | GRIA2 (0.44) | GRIA2SLC10A2MTNR1AMTNR1BADRA1D | |
| SCHEMBL2357409 | 0.88 | GRIA2 (0.35) | GRIA2GALR1SLC10A2ADRA1D | |
| SCHEMBL2353968 | 0.88 | GRIA2 (0.47) | GRIA2FFAR1FFAR4ADRA1D | |
| SCHEMBL2351722 | 0.88 | MAOA (0.35) | GRIA2MAOBADRA1D | |
| SCHEMBL2352846 | 0.88 | ADRA1D (0.42) | GRIA2SLC10A2ADRA1D | |
| SCHEMBL2353218 | 0.83 | ADRA1D (0.46) | GRIA2GALR1SLC10A2ADRA1D | |
| SCHEMBL2354007 | 0.78 | MMP2 (0.46) | NPC1MTNR1AMTNR1BADRA1D | |
| SCHEMBL2357167 | 0.76 | ADRA1D (0.37) | SLC10A2ADRA1D | |
| SCHEMBL2355589 | 0.74 | ADRA1D (0.40) | GRIA2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |