Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347270 | 0.87 | GRIA1 (0.35) | CA1CA2ABCC8KCNJ11ADRA1D | |
| SCHEMBL2355164 | 0.81 | CA1 (0.41) | CA1CA2ABCC8KCNJ11ADRA1D | |
| SCHEMBL2355322 | 0.81 | ADRA1D (0.45) | CA1CA2ADRA1DGRIA1GRIA2 | |
| SCHEMBL2354545 | 0.80 | ADRA1D (0.30) | ADRA1D | |
| SCHEMBL24075043 | 0.79 | CA1 (0.56) | CA1CA2ABCC8KCNJ11GRIA1 | |
| SCHEMBL13499159 | 0.79 | CA2 (0.43) | CA1CA2ABCC8KCNJ11ADRA1D | |
| SCHEMBL13499158 | 0.79 | CA2 (0.42) | CA1CA2ABCC8KCNJ11ADRA1D | |
| SCHEMBL4246184 | 0.79 | CA2 (0.42) | CA1CA2ABCC8KCNJ11ADRA1D | |
| Hydrochloric Acid SCHEMBL1003509 | 0.77 | CA2 (0.44) | CA1CA2ABCC8KCNJ11ADRA1D | |
| SCHEMBL2357167 | 0.76 | ADRA1D (0.37) | ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |