SCHEMBL235748

SCHEMBL235748

NCCc1cccc(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 11/20 1.00
DRD2 P14416 1/20 0.57
DRD1 P21728 1/20 0.57
IDO1 P14902 2/20 0.55
AGXT P21549 2/20 0.55
HTR2A P28223 2/20 0.54
CYP2A6 P11509 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
HTR6 P50406 2/20 0.50
HTR2C P28335 1/20 0.50
NOS1 P29475 1/20 0.47
MAOB P27338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL30914652 0.98 TAAR1 (0.96) TAAR1DRD2DRD1IDO1AGXT
Hydrochloric Acid SCHEMBL5214116 0.98 TAAR1 (0.96) TAAR1DRD2DRD1IDO1AGXT
SCHEMBL237142 0.87 TAAR1 (0.77) TAAR1IDO1AGXTCYP2A6HTR6
SCHEMBL4399626 0.85 TAAR1 (0.74) TAAR1IDO1AGXTSMN1; SMN2MAOB
SCHEMBL6183551 0.85 TAAR1 (0.74) TAAR1IDO1AGXTMAOB
Hydrochloric Acid SCHEMBL5234157 0.85 TAAR1 (0.74) TAAR1IDO1AGXTCYP2A6HTR6
SCHEMBL552962 0.84 TAAR1 (0.71) TAAR1IDO1AGXT
SCHEMBL659100 0.83 TAAR1 (0.70) TAAR1DRD2DRD1HTR2ACYP2A6
SCHEMBL7199505 0.82 TAAR1 (0.69) TAAR1IDO1AGXTSMN1; SMN2MAOB
SCHEMBL3401008 0.81 TAAR1 (0.68) TAAR1IDO1AGXTSMN1; SMN2LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894363-B Synthesis process of 6-bromo-1, 2,3, 4-tetrahydroisoquinoline 苏州艾缇克药物化学有限公司 2025-02-11 CN claimed
CN-116444598-B Ganoderic acid A derivative, its synthesis method and application in treating tumor 中国医学科学院药用植物研究所 2024-11-01 CN claimed
CN-118813253-A Preparation method of tin-based perovskite 南京工业大学 2024-10-22 CN claimed
CN-115141197-B 3-aromatic heterocycle substituted phenyl derivative and preparation method and application thereof 安徽医科大学 2024-03-26 CN claimed
CN-116444598-A Ganoderic acid A derivative, its synthesis method and application in treating tumor 中国医学科学院药用植物研究所 2023-07-18 CN claimed
CN-115894363-A Synthesis process of 6-bromo-1,2,3,4-tetrahydroisoquinoline 苏州艾缇克药物化学有限公司 2023-04-04 CN claimed
CN-115141197-A 3-aromatic heterocyclic substituted phenyl derivative and preparation method and application thereof 安徽医科大学 2022-10-04 CN claimed
CN-113512029-A Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2021-10-19 CN claimed
CN-110002930-B Method for hydrogenation reduction of alkenyl aromatic halogenated derivatives 浙江大学 2020-05-12 CN claimed
US-8574953-B2 Low temperature melt-processing of organic-inorganic hybrid INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-11-05 US claimed
US-20120126216-A1 LOW TEMPERATURE MELT-PROCESSING OF ORGANIC-INORGANIC HYBRID INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-05-24 US claimed
WO-2009056993-A2 A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-05-07 WO claimed
US-7291516-B2 Low temperature melt-processing of organic-inorganic hybrid INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-06 US claimed
US-20060234480-A1 Low temperature melt-processing of organic-inorganic hybrid INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-10-19 US claimed
US-7105360-B2 Low temperature melt-processing of organic-inorganic hybrid INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-09-12 US claimed
US-20030170918-A1 Low temperature melt-processing of organic-inorganic hybrid INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-09-11 US claimed
US-20260091147-A1 METHOD FOR DETECTING INNATE IMMUNE ACTION IN VIVO USING GPR84-PET THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIV (US) 2026-04-02 US disclosed
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2026-04-02 US disclosed
US-5260316-A Lipoxygenase inhibitor CIBA-GEIGY CORPORATION (US) 1993-11-09 US disclosed
EP-0526402-A1 Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors CIBA-GEIGY AG (CH) 1993-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS TFPI, F3, BTK TAAR1 1680/4885DRD2 2531/4885DRD1 2490/4885
US-20260091147-A1 METHOD FOR DETECTING INNATE IMMUNE ACTION IN VIVO USING GPR84-PET GPR84, GPR65, GPR88 TAAR1 128/4885DRD2 316/4885DRD1 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.