SCHEMBL23576342

SCHEMBL23576342

C=C(C)C(=O)O[C@@H]1C[C@H](C)CC[C@H]1C(C)=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
EPHX1 P07099 3/20 0.33
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
RAB9A P51151 1/20 0.30
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576343 1.00 ALDH1A1 (0.33) ALDH1A1EPHX1KDM4ENPC1POLB
SCHEMBL8775683 0.86 ALDH1A1 (0.35) ALDH1A1EPHX1ATMHPGD
SCHEMBL23576346 0.81 CHRM2 (0.36) ALDH1A1EPHX1HPGD
SCHEMBL465418 0.81 ALDH1A1 (0.34) ALDH1A1EPHX1
SCHEMBL23576350 0.81 CHRM2 (0.36) ALDH1A1EPHX1HPGD
SCHEMBL1320016 0.79 EPHX1 (0.55) ALDH1A1EPHX1KDM4EMAPTHPGD
SCHEMBL5354058 0.79 EPHX1 (0.55) ALDH1A1EPHX1KDM4EMAPTHPGD
SCHEMBL14559200 0.79 EPHX1 (0.55) ALDH1A1EPHX1KDM4EMAPTHPGD
SCHEMBL23494169 0.78 ALDH1A1 (0.38) ALDH1A1KDM4ENPC1POLBMAPT
SCHEMBL7794025 0.78 ALDH1A1 (0.30) ALDH1A1EPHX1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210198229-A1 FRAGRANCE AND FLAVOR MATERIALS FROM 1-(2-HYDROXY-4-METHYLCYCLOHEXYL)-ETHANONE TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198229-A1 FRAGRANCE AND FLAVOR MATERIALS FROM 1-(2-HYDROXY-4-METHYLCYCLOHEXYL)-ETHANONE TAS2R5, TAS2R50, TAS2R20 ALDH1A1 457/4885EPHX1 765/4885KDM4E 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.