Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577373 | 0.90 | UBE2M (0.47) | DRD2CCR2RBP4UBE2MDCUN1D1 | |
| SCHEMBL23605549 | 0.89 | DRD2 (0.46) | DRD2CCR2RBP4USP5CHRM4 | |
| SCHEMBL23577508 | 0.89 | GAA (0.46) | PARP10HSD11B1MGLLMAPK7CNR1 | |
| SCHEMBL23577528 | 0.85 | EPHX2 (0.41) | RBP4PARP10 | |
| SCHEMBL23578349 | 0.84 | RBP4 (0.49) | DRD2CCR2RBP4UBE2MDCUN1D1 | |
| SCHEMBL23578389 | 0.81 | RBP4 (0.47) | RBP4 | |
| SCHEMBL23605175 | 0.79 | PROKR1 (0.51) | — | |
| SCHEMBL23577488 | 0.79 | EGLN1 (0.47) | PARP10HSD11B1MGLLMAPK7CNR1 | |
| SCHEMBL23577378 | 0.79 | GAA (0.45) | PARP10HSD11B1MGLLMAPK7CNR1 | |
| SCHEMBL23577339 | 0.78 | MAPK7 (0.48) | PARP10HSD11B1MGLLMAPK7CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021130723-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |