SCHEMBL23578423

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23588257	0.96	SPHK1 (0.58)	SPHK1S1PR1ALDH1A1NPC1MAPT
	SCHEMBL25297027	0.86	L3MBTL1 (0.46)	SPHK1ALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL29843966	0.86	L3MBTL1 (0.46)	SPHK1ALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL23578433	0.85	ACACB (0.57)	ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
	SCHEMBL23588102	0.85	SPHK1 (0.48)	SPHK1S1PR1ALDH1A1NPC1MAPT
	SCHEMBL25296476	0.84	HDAC8 (0.46)	SPHK1S1PR1ALDH1A1S1PR5S1PR4
	SCHEMBL23588038	0.83	ALDH1A1 (0.43)	SPHK1S1PR1ALDH1A1MAPTNFKB1
	SCHEMBL23578022	0.82	S1PR4 (0.51)	S1PR1NPC1RAB9AS1PR5S1PR4
	SCHEMBL25802136	0.82	MAPT (0.53)	ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
	SCHEMBL25295300	0.80	TSHR (0.63)	ALDH1A1NPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.