Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143862 | 0.82 | ALDH1A1 (0.46) | L3MBTL1KMT2AALDH1A1ATMCHRM2 | |
| SCHEMBL13570508 | 0.80 | BCHE (0.51) | L3MBTL1POLBKMT2AKDM4EUSP2 | |
| SCHEMBL2143801 | 0.76 | ALDH1A1 (0.47) | ALDH1A1BCHEPRMT5WDR77GPBAR1 | |
| SCHEMBL2143837 | 0.73 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1ATMPRMT5WDR77 | |
| SCHEMBL2143791 | 0.73 | POLB (0.53) | L3MBTL1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL2143989 | 0.67 | PDK1 (0.59) | L3MBTL1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL2143811 | 0.67 | PDK1 (0.48) | L3MBTL1KMT2AALDH1A1ATMGPBAR1 | |
| SCHEMBL2143714 | 0.67 | POLB (0.56) | L3MBTL1POLBKMT2AUSP2ALDH1A1 | |
| SCHEMBL2143986 | 0.67 | ALDH1A1 (0.47) | POLBUSP2ALDH1A1MAPTMAPK1 | |
| SCHEMBL2143810 | 0.67 | ALDH1A1 (0.44) | POLBALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080264-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | claimed |