Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357967 | 0.80 | L3MBTL1 (0.39) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL2143801 | 0.75 | ALDH1A1 (0.47) | BCHEALDH1A1EGLN1 | |
| SCHEMBL2237500 | 0.73 | BCHE (0.67) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL26241625 | 0.73 | BCHE (0.74) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| Hydrochloric Acid SCHEMBL19437125 | 0.72 | BCHE (0.66) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL1787096 | 0.72 | KDM4E (0.68) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL26241636 | 0.70 | BCHE (0.70) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL9976030 | 0.69 | BCHE (0.69) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL14213275 | 0.69 | KDM4E (0.59) | BCHEKDM4ETP53L3MBTL1ALOX12 | |
| SCHEMBL2143758 | 0.69 | BCHE (0.49) | BCHEKDM4ETP53L3MBTL1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | Polichem SA (LU) | 2012-11-07 | — | — | EP | claimed |