Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358014 | 0.90 | ATM (0.64) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL8478316 | 0.84 | ATM (0.58) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL8311827 | 0.82 | ATM (0.56) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL29254343 | 0.82 | ATM (0.56) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL2329814 | 0.81 | ATM (0.55) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL10716596 | 0.81 | ATM (0.55) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL24188 | 0.80 | TDP1 (0.56) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL2238176 | 0.80 | TDP1 (0.56) | ATMGAAHSP90AA1NPC1RAB9A | |
| Water SCHEMBL7994044 | 0.79 | ATM (0.53) | ATMGAAHSP90AA1NPC1RAB9A | |
| SCHEMBL28238806 | 0.78 | CES2 (0.56) | ATMGAAHSP90AA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106995394-B | The preparation method of β -one sulfones | 齐齐哈尔大学 | 2018-09-07 | — | — | CN | claimed |
| CN-107876092-A | The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107417719-A | A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2017-12-01 | — | — | CN | claimed |
| CN-106995394-A | The preparation method of β ketone sulfones | 齐齐哈尔大学 | 2017-08-01 | — | — | CN | claimed |
| CN-106995394-B | The preparation method of β -one sulfones | 齐齐哈尔大学 | 2018-09-07 | — | — | CN | disclosed |
| CN-106995394-A | The preparation method of β ketone sulfones | 齐齐哈尔大学 | 2017-08-01 | — | — | CN | disclosed |
| CN-101239994-B | Transition metal complex having diphosphine compound as ligand | TAKEDA PHARMACEUTICAL | 2015-05-13 | — | — | CN | disclosed |
| EP-1568701-B1 | TRANSITION METAL COMPLEX HAVING DIPHOSPHINE COMPLEX AS LIGAND | TAKEDA PHARMACEUTICAL (JP) | 2010-01-20 | — | — | EP | disclosed |
| JP-2006232788-A | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-CHLORO-3-HYDROXYL-3,N-DIPHENYL-PROPANOIC ACID AMIDE | NIPPON KAYAKU CO LTD | 2006-09-07 | — | — | JP | disclosed |
| EP-1622903-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1553170-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORPORATION (JP) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004094421-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| EP-1418237-A2 | Anti-Kazlauskas lipases | Bayer Chemicals AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| CN-1042639-C | Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin | DSM NV (NL) | 1999-03-24 | — | — | CN | disclosed |
| CN-1125954-A | Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin | DSM NV (NL) | 1996-07-03 | — | — | CN | disclosed |
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |