Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579898 | 0.86 | DCTPP1 (0.60) | MAPTATMDCTPP1LMNAKMT2A | |
| SCHEMBL23580402 | 0.81 | ALDH1A1 (0.47) | MAPTPOLBATMDCTPP1LMNA | |
| SCHEMBL23608127 | 0.79 | DHODH (0.46) | DHODHKMT2AL3MBTL1MEN1TSHR | |
| SCHEMBL23580790 | 0.74 | CFTR (0.48) | MAPTDCTPP1LMNACASP6ALDH1A1 | |
| SCHEMBL23579734 | 0.74 | AR (0.47) | DCTPP1LMNAALDH1A1ARCFTR | |
| SCHEMBL23579863 | 0.73 | DPP4 (0.45) | MAPTPOLBLMNAKMT2AL3MBTL1 | |
| SCHEMBL23579897 | 0.71 | DCTPP1 (0.61) | MAPTPOLBATMDCTPP1KMT2A | |
| SCHEMBL15910675 | 0.70 | MAPT (0.49) | MAPTPOLBLMNAKMT2AL3MBTL1 | |
| SCHEMBL3281052 | 0.70 | MAPT (0.61) | MAPTPOLBLMNAKMT2AL3MBTL1 | |
| SCHEMBL23579989 | 0.70 | BUB1 (0.37) | MAPTPOLBDCTPP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339150-B2 | Benzimidazole compounds as HDAC6 inhibitors | ONKURE, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220041584-A1 | BENZIMIDAZOLE COMPOUNDS AS HDAC6 INHIBITORS | ONKURE, INC. (US) | 2022-02-10 | — | — | US | disclosed |
| WO-2021133957-A1 | BENZIMIDAZOLE COMPOUNDS AS HDAC6 INHIBITORS | ONKURE, INC. (US) | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041584-A1 | BENZIMIDAZOLE COMPOUNDS AS HDAC6 INHIBITORS | HDAC6, HDAC1, HDAC11 | MAPT 462/4885POLB 556/4885ATM 2491/4885 |
| US-11339150-B2 | Benzimidazole compounds as HDAC6 inhibitors | HDAC6, HDAC1, HDAC11 | MAPT 462/4885POLB 556/4885ATM 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.