Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358363 | 1.00 | ACHE (0.33) | ACHEALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL25349137 | 0.75 | — | — | |
| SCHEMBL27651560 | 0.75 | — | — | |
| SCHEMBL25349142 | 0.75 | — | — | |
| SCHEMBL31661847 | 0.74 | — | — | |
| SCHEMBL2358352 | 0.66 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10641772 | 0.64 | — | — | |
| SCHEMBL22791341 | 0.63 | CYP1A2 (0.32) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL5736419 | 0.63 | — | — | |
| SCHEMBL10338673 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350060-A2 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd (KR) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010056022-A2 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2010-05-20 | — | — | WO | disclosed |