SCHEMBL2358352

SCHEMBL2358352

CC1CCC(N2CCCC2(N)C(=O)O)CC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALOX15 P16050 1/20 0.35
CPB2 Q96IY4 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5492945 0.80 HSD11B1 (0.34) ALOX15
SCHEMBL28833356 0.67 FFAR3 (0.32)
SCHEMBL28833355 0.67 FFAR3 (0.32)
SCHEMBL29232716 0.67 AGTR2 (0.32) ALDH1A1KDM4EALOX15
SCHEMBL29232718 0.67 AGTR2 (0.32) ALDH1A1KDM4EALOX15
SCHEMBL1062175 0.67 GRM2 (0.31)
SCHEMBL28611997 0.67 GRM2 (0.31)
SCHEMBL2358355 0.66 ACHE (0.33) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL2358363 0.66 ACHE (0.33) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL10725073 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350060-A2 MELANOCORTIN RECEPTOR AGONISTS LG Life Sciences Ltd (KR) 2011-08-03 EP disclosed
WO-2010056022-A2 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2010-05-20 WO disclosed