Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.57 |
| ▸ | CETP | P11597 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 3/20 | 0.50 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316963 | 0.94 | PTPN2 (0.64) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL2358470 | 0.89 | PTPN2 (0.48) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL13930857 | 0.88 | KDM4E (0.61) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL2319255 | 0.83 | EPHX2 (0.60) | PTPN1NAMPTALDH1A1 | |
| SCHEMBL16825852 | 0.82 | FPR2 (0.63) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL13930870 | 0.82 | GPR119 (0.58) | PTPN2PTPN1PTPN6CETPKDM4E | |
| Hydrochloric Acid SCHEMBL2318668 | 0.82 | EPHX2 (0.58) | PTPN1NAMPTALDH1A1 | |
| SCHEMBL13930863 | 0.81 | PTPN2 (0.57) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL13930867 | 0.81 | PTPN2 (0.57) | PTPN2PTPN1PTPN6CETPKDM4E | |
| SCHEMBL13930876 | 0.81 | CETP (0.65) | PTPN2PTPN1PTPN6CETPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |