Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.57 |
| ▸ | GLS | O94925 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439589 | 0.93 | PTPN2 (0.52) | PTPN2PTPN1PTPN6GLSSTS | |
| SCHEMBL13930870 | 0.89 | GPR119 (0.58) | PTPN2PTPN1PTPN6GLSCETP | |
| SCHEMBL16825852 | 0.89 | FPR2 (0.63) | PTPN2PTPN1PTPN6GLSCETP | |
| SCHEMBL4965158 | 0.89 | L3MBTL1 (0.67) | PTPN2PTPN1PTPN6GLSCETP | |
| SCHEMBL13930863 | 0.88 | PTPN2 (0.57) | PTPN2PTPN1PTPN6GLSCETP | |
| SCHEMBL13930857 | 0.88 | KDM4E (0.61) | PTPN2PTPN1PTPN6GLSSTS | |
| SCHEMBL1934732 | 0.88 | USP30 (0.56) | PTPN2PTPN1PTPN6GLSCETP | |
| SCHEMBL13930859 | 0.87 | ALDH1A1 (0.66) | PTPN2PTPN1PTPN6GLSSTS | |
| SCHEMBL13930868 | 0.87 | EPHX2 (0.61) | PTPN2PTPN1PTPN6GLSSTS | |
| SCHEMBL5778694 | 0.86 | GPR119 (0.60) | PTPN2PTPN1PTPN6GLSCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048291-A1 | Novel Piperidine-4-Acetic Acid Derivatives and Their Use | EUROSCREEN S.A. (BE) | 2009-02-19 | — | — | US | disclosed |
| US-20090048291-A1 | Novel Piperidine-4-Acetic Acid Derivatives and Their Use | EUROSCREEN S.A. (BE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048291-A1 | Novel Piperidine-4-Acetic Acid Derivatives and Their Use | ALDH1A1, ABAT, ALDH18A1 | PTPN2 4672/4885PTPN1 4736/4885PTPN6 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.