Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703596 | 0.82 | KDR (0.52) | PDGFRAPDGFRBMETFGFR2KDR | |
| SCHEMBL21769162 | 0.82 | MET (0.56) | PDGFRAPDGFRBMETFGFR2KDR | |
| SCHEMBL21769156 | 0.81 | MET (0.71) | PDGFRAPDGFRBMETFGFR2 | |
| SCHEMBL22104168 | 0.78 | FGFR2 (0.58) | PDGFRAPDGFRBFGFR2KDRSRC | |
| SCHEMBL7480589 | 0.78 | FGFR2 (0.73) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL29577001 | 0.78 | PDGFRA (0.57) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL18163409 | 0.78 | PDGFRA (0.57) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL21185552 | 0.78 | PDGFRB (0.57) | PDGFRAPDGFRBFGFR2KDRSRC | |
| SCHEMBL29576571 | 0.78 | PDGFRB (0.57) | PDGFRAPDGFRBFGFR2KDRSRC | |
| SCHEMBL21769414 | 0.77 | FGFR2 (0.54) | PDGFRAPDGFRBMETFGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |