Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23977293 | 0.75 | — | — | |
| SCHEMBL19198264 | 0.75 | — | — | |
| SCHEMBL19198356 | 0.69 | — | — | |
| SCHEMBL5450844 | 0.68 | — | — | |
| SCHEMBL13292492 | 0.68 | — | — | |
| SCHEMBL10028023 | 0.66 | CARM1 (0.36) | CARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL9906473 | 0.63 | — | — | |
| SCHEMBL6284178 | 0.62 | PER2 (0.38) | CARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL9906474 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL22518684 | 0.61 | CARM1 (0.39) | CARM1PRMT6PRMT8PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842459-A1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | ImmunoGen, Inc. (US) | 2021-06-30 | — | — | EP | disclosed |