⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628172 | 0.81 | — | — | |
| SCHEMBL8671012 | 0.79 | FDPS (0.47) | — | |
| SCHEMBL5258366 | 0.79 | — | — | |
| SCHEMBL1005554 | 0.78 | — | — | |
| SCHEMBL5871559 | 0.76 | — | — | |
| SCHEMBL14834500 | 0.72 | — | — | |
| SCHEMBL659365 | 0.71 | — | — | |
| SCHEMBL1680371 | 0.71 | — | — | |
| SCHEMBL357852 | 0.71 | — | — | |
| SCHEMBL5548976 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118434-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS KINASE JAK-2 INHIBITORS | CELON PHARMA S.A. (PL) | 2015-08-13 | — | — | WO | disclosed |
| EP-2349260-A1 | JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES | Incyte Corporation (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010039939-A1 | JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES | INCYTE CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |
| CN-1489577-A | Cyanothioacetamide derivatives and process for preparing same | �ձ�������ʽ���� | 2004-04-14 | — | — | CN | disclosed |