⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834500 | 0.86 | — | — | |
| SCHEMBL8671012 | 0.85 | FDPS (0.47) | — | |
| SCHEMBL1151196 | 0.80 | — | — | |
| Bromide SCHEMBL17582405 | 0.78 | — | — | |
| SCHEMBL1628172 | 0.77 | — | — | |
| SCHEMBL841789 | 0.76 | — | — | |
| SCHEMBL11129960 | 0.76 | — | — | |
| SCHEMBL1680371 | 0.76 | — | — | |
| SCHEMBL257550 | 0.76 | — | — | |
| SCHEMBL5548976 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517440-A | Fungicidal 3- { phenyl [ (heterocyclylmethoxy) imino ] methyl } -oxadiazolone derivatives | BAYER CROPSCIENCE AG | 2016-04-20 | — | — | CN | disclosed |
| CN-104755476-A | Method for producing compound | SUMITOMO CHEMICAL CO | 2015-07-01 | — | — | CN | disclosed |
| CN-104744446-A | Hetero-aromatic compound and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-07-01 | — | — | CN | disclosed |
| CN-104619698-A | Pyrrolidine derivatives and their use as complement pathway modulators | NOVARTIS AG | 2015-05-13 | — | — | CN | disclosed |
| CN-104583218-A | Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | BRISTOL MYERS SQUIBB CO | 2015-04-29 | — | — | CN | disclosed |
| CN-104478869-A | Oxazolidinone compound and application thereof to drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-04-01 | — | — | CN | disclosed |
| CN-104039769-A | Fungicidal 3-[(1,3-thiazol-4-ylmethoxyimino)(phenyl)methyl]-2-substituted-1,2,4-oxadiazol-5(2h)-one Derivatives | BAYER IP GMBH | 2014-09-10 | — | — | CN | disclosed |
| CN-103649079-A | Hepatitis C inhibitor and application thereof | ABBVIE INC | 2014-03-19 | — | — | CN | disclosed |
| CN-101163693-B | Antibacterial piperidine derivatives | ASTRAZENECA AB | 2013-03-06 | — | — | CN | disclosed |
| CN-102906092-A | Certain triazolopyridine compounds and triazolopyrazine compounds, compositions thereof and methods of use thereof | HUTCHISON MEDIPHARMA LTD | 2013-01-30 | — | — | CN | disclosed |
| US-7071201-B2 | Serotonin antagonism; muscle relaxant for myotonia; such as 1-(1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)-7-methoxy-1,2,3,4 -tetrahydroquinoline | EISAI CO., LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-0976732-B1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6579881-B2 | Indoles | EISAI CO., LTD. (JP) | 2003-06-17 | — | — | US | disclosed |
| US-6448243-B1 | SEROTONIN ANTAGONIST FOR TREATING, AMELIORATING AND PREVENTING SPASTIC PARALYSIS OR CENTRAL MUSCLE RELAXANTS FOR AMELIORATING MYOTONIA | EISAI CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| US-20020086999-A1 | Certain quinoline derivatives | EISAI CO., LTD. | 2002-07-04 | — | — | US | disclosed |
| US-20020019531-A1 | Indoles | EISAI CO., LTD. | 2002-02-14 | — | — | US | disclosed |
| EP-0976732-A1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1016173-B | NOVEL (ARYL OR HETERVAROMATIC METHYL) -2,2'-BI-1H-IMIDAZOLES PROCESS | MERRELL DOW PHARMA (US) | 1992-04-08 | — | — | CN | disclosed |
| CN-1034718-A | Novel (aryl or heteroaryl methyl)-2,2 '-two-1H-imidazoles | MERRELL DOW PHARMA (US) | 1989-08-16 | — | — | CN | disclosed |
| CN-1032007-A | Prepare the method for halogen alkyl thiazole and the halogen alkyl thiazole of preparation thereof | PFIZER (US) | 1989-03-29 | — | — | CN | disclosed |