Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011959 | 0.85 | MAP3K5 (0.47) | ALDH1A1HSD17B10GAAHPGDALOX15 | |
| SCHEMBL28965697 | 0.81 | SIRT6 (0.44) | KDM4EALDH1A1GAAMAPTHDAC1 | |
| SCHEMBL23577773 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| Hydrochloric Acid SCHEMBL23578246 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL30184152 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL23577945 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL23591052 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| Hydrochloric Acid SCHEMBL23578377 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| Hydrochloric Acid SCHEMBL30183831 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL23590548 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130731-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |