Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578343 | 0.82 | SIRT6 (0.44) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL23011959 | 0.81 | MAP3K5 (0.47) | ALDH1A1HTTLMNAHDAC3HDAC4 | |
| SCHEMBL23590708 | 0.81 | KDM4E (0.42) | ALDH1A1HTTHDAC3HDAC4HDAC1 | |
| SCHEMBL30183682 | 0.79 | SIRT6 (0.43) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL23591009 | 0.77 | ALDH1A1 (0.40) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL28965721 | 0.76 | ALDH1A1 (0.40) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL29267763 | 0.76 | SIRT6 (0.40) | SIRT6ALDH1A1HTTLMNAHDAC3 | |
| SCHEMBL23577603 | 0.75 | MAPT (0.45) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL23577725 | 0.75 | SIRT6 (0.40) | SIRT6ALDH1A1HTTLMNAPDGFRB | |
| SCHEMBL23578549 | 0.75 | SIRT6 (0.40) | SIRT6ALDH1A1HTTLMNAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |