SCHEMBL235910

SCHEMBL235910

CC(C)CCCOC(=O)c1ccc(Br)cc1C(=O)OCCCC(C)C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
HPGD P15428 3/20 0.44
TSHR P16473 6/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.42
PTPN2 P17706 3/20 0.40
PTPN6 P29350 2/20 0.40
PTPN11 Q06124 2/20 0.40
PTPN1 P18031 2/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627848 0.95 TSHR (0.54) ATMHPGDTSHRTDP1L3MBTL1
SCHEMBL4628055 0.95 ATM (0.46) ATMHPGDTSHRTDP1L3MBTL1
SCHEMBL235035 0.94 TSHR (0.47) ATMHPGDTSHRTDP1L3MBTL1
SCHEMBL15675248 0.91 HPGD (0.46) ATMHPGDTSHRTDP1L3MBTL1
SCHEMBL4625900 0.88 ALDH1A1 (0.43) ATMHPGDTSHRTDP1L3MBTL1
SCHEMBL4628590 0.84 ESR1 (0.43) TSHRTDP1L3MBTL1MAPK1TP53
SCHEMBL20695623 0.84 KMT2A (0.47) TSHRTDP1L3MBTL1MAPK1TP53
SCHEMBL4626478 0.84 TSHR (0.45) TSHRTDP1L3MBTL1MAPK1TP53
SCHEMBL5275453 0.84 TSHR (0.56) TSHRTDP1L3MBTL1MAPK1TP53
SCHEMBL4628603 0.83 TSHR (0.54) ATMHPGDTSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 EP claimed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US claimed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP claimed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP claimed
EP-1283222-B9 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-11-13 EP disclosed
EP-1283222-B2 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-03-27 EP disclosed
EP-2636688-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS TOHO TITANIUM CO LTD (JP) 2016-11-16 EP disclosed
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
EP-1921092-B1 CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER USING THOSE TOHO TITANIUM CO LTD (JP) 2013-10-02 EP disclosed
EP-2636688-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS Toho Titanium Co., Ltd. (JP) 2013-09-11 EP disclosed
US-20040077488-A1 Polymerization catalyst for olefins and process for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2004-04-22 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030153454-A1 Solid catalyst ingredient and catalyst each for olefin polymerization and propylene block copolymer TOHO TITANIUM CO., LTD. (JP) 2003-08-14 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX ATM 4248/4885HPGD 9/4885TSHR 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.