SCHEMBL21294760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL935958	0.82	MEN1 (0.56)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL7564964	0.79	IDO1 (0.49)	ACP3MAPTIDO1POLBMAOB
	SCHEMBL10784114	0.78	TAAR1 (0.56)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL21306789	0.78	HTR2A (0.53)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL6865758	0.78	MEN1 (0.62)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL4941532	0.77	MEN1 (0.55)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL21294907	0.77	MEN1 (0.50)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL31738386	0.76	EPHX1 (0.54)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL29935522	0.76	MEN1 (0.65)	ACP3MEN1KMT2AMAPTTAAR1
	SCHEMBL11808569	0.76	MEN1 (0.60)	ACP3MEN1KMT2AMAPTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.