SCHEMBL2359477

SCHEMBL2359477

C=CC(=O)OC(CC)[Si](C)(C)OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14825094 0.87 TSHR (0.36) TSHRHPGD
SCHEMBL28174418 0.87 TSHR (0.38) TSHRHPGD
SCHEMBL2553653 0.85 TSHR (0.39) TSHRHPGD
SCHEMBL18918481 0.84 TSHR (0.37) TSHRHPGD
SCHEMBL3832655 0.83 TSHR (0.36) TSHRHPGD
SCHEMBL139100 0.81 TSHR (0.35) TSHRHPGD
SCHEMBL374775 0.81 TSHR (0.38) TSHRHPGD
SCHEMBL29249892 0.81 TSHR (0.36) TSHRHPGD
SCHEMBL5838258 0.80 TSHR (0.39) TSHRHPGD
SCHEMBL3478417 0.79 TSHR (0.33) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507622-B2 Polymerizable compositions ROHM AND HAAS COMPANY (US) 2013-08-13 US disclosed
EP-2236527-B1 Improved polymerizable compostions ROHM & HAAS (US) 2011-08-17 EP disclosed
EP-2236528-B1 Improved polymerizable compositions ROHM & HAAS (US) 2011-08-03 EP disclosed
US-7834120-B2 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
EP-2236528-A1 Improved polymerizable compositions Rohm and Haas Company (US) 2010-10-06 EP disclosed
EP-2236527-A1 Improved polymerizable compostions Rohm and Haas Company (US) 2010-10-06 EP disclosed
US-20100249365-A1 Polymerizable compositions LEMONDS ANDREW 2010-09-30 US disclosed
US-20100249348-A1 Polymerizable compositions ROHM AND HAAS COMPANY 2010-09-30 US disclosed
EP-1645560-B1 Monofunctional monomer having cage oligosiloxane structure and method of making SHINETSU CHEMICAL CO (JP) 2008-05-28 EP disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed
US-6566549-B1 Forming oligomers of vinyl acetate and oligomers of vinyl alcohol; fully saturated and terminally unsaturated oligomers ROHM AND HAAS COMPANY 2003-05-20 US disclosed
US-20020111448-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-08-15 US disclosed
US-20020082371-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-06-27 US disclosed
EP-1010706-A2 Continuous polymerization process and products therefrom ROHM AND HAAS COMPANY (US) 2000-06-21 EP disclosed