SCHEMBL139100

SCHEMBL139100

C=CC(=O)OC(CC)[Si](C)(C)OCC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
HPGD P15428 1/20 0.34
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16536922 0.87 TSHR (0.36) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL134911 0.86 TSHR (0.35) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL18918481 0.86 TSHR (0.37) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL109906 0.84 TSHR (0.36) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL3832655 0.84 TSHR (0.36) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL16537303 0.84 TSHR (0.44) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL16536935 0.83 TSHR (0.33) TSHRHPGD
SCHEMBL374775 0.83 TSHR (0.38) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL5838258 0.82 TSHR (0.39) TSHRHPGDALDH1A1TP53CYP3A4
SCHEMBL1067079 0.81 TSHR (0.34) TSHRHPGDALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
CN-119584936-A Curable composition for producing transparent orthodontic accessories 舒万诺知识产权公司 2025-03-07 CN disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-01-09 US disclosed
EP-4464301-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER Kuraray Noritake Dental Inc. (JP) 2024-11-20 EP disclosed
EP-4445891-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-10-16 EP disclosed
EP-3507011-B1 SHAPED GEL ARTICLES AND SINTERED ARTICLES PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-26 EP disclosed
US-11884550-B2 Shaped gel articles and sintered articles prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-30 US disclosed
CN-117377722-A Rubber composition and tire 株式会社普利司通 2024-01-09 CN disclosed
CN-117136204-A Polysiloxane resin and use thereof 株式会社钟化 2023-11-28 CN disclosed
US-7834120-B2 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
EP-1645560-B1 Monofunctional monomer having cage oligosiloxane structure and method of making SHINETSU CHEMICAL CO (JP) 2008-05-28 EP disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed
EP-1323779-A1 Foamed polyolefin sheets with improved property spectrum Borealis GmbH (AT) 2003-07-02 EP disclosed
EP-0695783-B1 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR (JP) 2000-02-02 EP disclosed
US-5738976-A HEAT RESISTANT, STORAGE STABLE POLYSILSESQUIOXANE MIXED WITH PHOTOSENSITIZER; PHOTORESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-04-14 US disclosed
US-5650475-A VINYL POLYMERS WITH BLOCKED CARBOXY, SILANOL, EPOXY, HYDROLYZED SILYL AND ACID ANHYDRIDES IN SOLVENTS MAZDA MOTOR CORPORATION (JP) 1997-07-22 US disclosed
EP-0695783-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition Mazda Motor Corporation (JP) 1996-02-07 EP disclosed
EP-0688841-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR CORPORATION (JP) 1995-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B TSHR 4352/4885HPGD 2520/4885ALDH1A1 1530/4885
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE CAD, SEM1, CAPZA1 TSHR 3083/4885HPGD 1522/4885ALDH1A1 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.