SCHEMBL18918481

SCHEMBL18918481

C=CC(=O)OC(CC)[Si](C)(C)O[Si](C)(C)C(CC)OC(=O)C=C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.37
HPGD P15428 1/20 0.36
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374775 0.93 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3478417 0.90 TSHR (0.33) TSHRHPGD
SCHEMBL3832655 0.87 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL139100 0.86 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5838258 0.85 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2359477 0.84 TSHR (0.38) TSHRHPGD
SCHEMBL9788927 0.83 TSHR (0.33) TSHRHPGD
SCHEMBL9245895 0.82 TSHR (0.32) TSHRHPGD
SCHEMBL1717354 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5839195 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049184-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-19 US disclosed
US-20230049921-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-02-16 US disclosed
EP-4089147-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING Shin-Etsu Chemical Co., Ltd. (JP) 2022-11-16 EP disclosed
EP-3178876-B1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSION AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD SHINETSU CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10227453-B2 Silicone rubber composition and cured product thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-03-12 US disclosed
EP-3178876-A1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSON AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2017-06-14 EP disclosed
EP-3178885-A1 SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF Shin-Etsu Chemical Co., Ltd. (JP) 2017-06-14 EP disclosed
US-20170158821-A1 SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-08 US disclosed
US-20170158859-A1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSION AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049184-A1 CURABLE COMPOSITION AND INK FOR INK-JET PRINTING SEM1, COL1A1, HTR3D TSHR 3974/4885HPGD 3457/4885ALDH1A1 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.