Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23595660 | 0.78 | GRIN1 (0.42) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL23595643 | 0.75 | GRIN1 (0.36) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL23595772 | 0.72 | HTT (0.35) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL23595536 | 0.71 | LMNA (0.39) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL4759700 | 0.70 | ALDH1A1 (0.35) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL9663044 | 0.70 | ALDH1A1 (0.35) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL23595995 | 0.69 | LMNA (0.35) | SLC6A4GRIN1GRIN2ALMNAOPRK1 | |
| SCHEMBL104646 | 0.67 | — | — | |
| SCHEMBL23595640 | 0.67 | LMNA (0.33) | GRIN1GRIN2ALMNAGRIN2BTSHR | |
| SCHEMBL23579017 | 0.67 | GRIN1 (0.48) | SLC6A4GRIN1GRIN2ALMNAOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021134086-A1 | ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2021-07-01 | — | — | WO | disclosed |