Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663044 | 1.00 | ALDH1A1 (0.35) | ALDH1A1POLBGRIN1GRIN2ASLC6A4 | |
| SCHEMBL8624879 | 0.79 | ALDH1A1 (0.33) | ALDH1A1POLBGRIN1GRIN2ASLC6A4 | |
| SCHEMBL7495354 | 0.78 | ALDH1A1 (0.34) | ALDH1A1POLBTSHR | |
| SCHEMBL11342163 | 0.74 | CDC25A (0.34) | ALDH1A1 | |
| SCHEMBL18972428 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8622849 | 0.71 | — | — | |
| SCHEMBL11457549 | 0.71 | GRIN1 (0.34) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL104646 | 0.70 | — | — | |
| SCHEMBL23596012 | 0.70 | SLC6A4 (0.33) | ALDH1A1POLBGRIN1GRIN2ASLC6A4 | |
| SCHEMBL2691988 | 0.69 | TRIM24 (0.36) | ALDH1A1POLBGRIN1GRIN2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871776-A2 | FUSED THIENO[2,3-B]PYRIDINE AND THIAZOLO[5,4-B]PYRIDINE COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006098961-A2 | FUSED THIENO [2, 3-B] PYRIDINE AND THIAZOLO [5, 4-B] PYRIDINE COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2006-09-21 | — | — | WO | disclosed |