Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030544 | 0.89 | BRD4 (0.46) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL12261421 | 0.83 | KDM4E (0.45) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL29385499 | 0.83 | KDM4E (0.45) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL1274286 | 0.83 | ALDH1A1 (0.55) | KDM4EGAAACHEALDH1A1CYP1A2 | |
| SCHEMBL12310550 | 0.81 | TUBB4A (0.39) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL21098798 | 0.81 | MAOA (0.38) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL6816982 | 0.81 | KDM4E (0.57) | KDM4EGAASMN1; SMN2ACHEALDH1A1 | |
| SCHEMBL1274254 | 0.78 | BRD4 (0.38) | KDM4EGAASMN1; SMN2SRD5A1ALDH1A1 | |
| SCHEMBL23599942 | 0.78 | CYP24A1 (0.42) | MAOAKDM4EGAASMN1; SMN2ACHE | |
| SCHEMBL29483405 | 0.76 | SRD5A1 (0.37) | SRD5A1L3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129827-A1 | BENZO FUSED RING-BASED COMPOUND | 南京明德新药研发有限公司 | 2021-07-01 | — | — | WO | disclosed |